Trepanation may refer to:
- Trepanation, form of surgery in which a hole is bored into the skull.
- Trepanation (album), the first American Head Charge album.
- Trepanation, a technique used by Bomb Disposal units, in which a bore is cut into the sidewall of a bomb and the explosive contents are extracted through a combination of steam and acid bath liquification of bomb contents.
Trepan may refer to:
- Trepan, a rock-boring tool used for sinking mine shafts.
- Trepan, a kind of industrial drill bit, commonly used to bore large diameter holes in metal and sometimes referred to as a BTA drill. The drill characteristically leaves a core.
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